Further observations on a pedigree of the oral-facial-digital syndrome.

Case III.2. This patient was born in 1907. No evidence of any of the features of the syndrome was obtained in the antecedent or collateral family history. On examination she was found to be edentulous and we were unable to find any record ofher natural dentition. Her tongue had a bifid tip and there was a large hamartoma on the right border (Fig. 2). She reported the removal of a similar lump from the left border in her childhood. On inspection a scar corresponding to that excision could be seen. Numerous small extra frenula were present in the vestibule between her lower lip and the alveolar ridge. There was a bony, hard swelling on the anterior palate. This had been present for at least 10 years, as it was recorded on the fitting surface of her denture. She had mild ocular hypertelorism. There were no digital abnormalities, and no other physical features associated with this syndrome were found. Fingerprints showed 6 ulnar loops (summed ridge count 55) and 4 arches (ridge count 0), but palm patterns were normal.